Friday, April 16, 2010

Psilicon Valley

Psilicon Valley

http://www.metroactive.com/features/psychedelics.html

This weekend, psychedelic explorers, academics and medical
professionals gather in San Jose to discuss 'Psychedelic Science in
the 21st Century.'

April 14, 2010
by Jessica Fromm

INTERNET PIONEER John Gilmore, one of Sun Microsystems' first
employees and co-founder of the free-software firm Cygnus Software,
says psychedelic drugs have been an essential tool in his life's work.

Before he made his millions, Gilmore was a journeyman programmer who
had moved to Silicon Valley from the East Coast in 1978. He says he
grew up believing in absolute truth, and that the world was just a
puzzle to be solved through logic and reason. Then he started
experimenting with drugs.

"My experiences with psychedelics convinced me that there was more
mystery in the world than that," he says, "and that our perceptions
are not as closely matched to reality as we believe."

He says he was stunned by the realization that "having a small amount
of a particular chemical in your bloodstream can change your
perceptions of the world.

"It sort of taught me that our relationship to reality is a little
bit fuzzy. It's mediated through our senses and through our
expectations. That knowledge has helped me puzzle my way through a
bunch of situations in both programming and business, sort of not
taking the obvious at face value but looking around the corner to
see, well, how does it look from that angle?"

Gilmore is responsible for a well-known saying about the nature of
the Internet: "The Net interprets censorship as damage and routes
around it." He credits his mind-expanding experiences with this
intellectual tendency to turn things on their head to find a solution.

He says he has taken drugs when confronting big life decisions­moving
to a new town, taking a new job, breaking up a relationship­because
they help him see things in a different light. "Having had the
experience, I could then use the knowledge I'd learned in everyday
life," he says.

A self-described "civil libertarian millionaire eccentric," Gilmore
now occupies himself as a philanthropist and outspoken proponent for
the end of the war on drugs. He is also a board member and major
contributor to the Multidisciplinary Association for Psychedelic
Studies (MAPS), a Santa Cruz–based nonprofit committed to
mainstreaming the medical use of psychedelic drugs, which is hosting
a national conference in San Jose this weekend.

For the past 24 years, MAPS has been facilitating and sponsoring
medical research into the benefits and risks of alternative
substances such as LSD, ecstasy, psilocybin mushrooms and the
Amazonian vine ayahuasca. This week's conference, "Psychedelic
Science in the 21st Century," will be the biggest international
psychedelic science gathering in almost two decades.

More than 800 psychedelic researchers, health-care professionals,
psychotherapists and spiritual leaders will converge on San Jose
April 15–18 at the Holiday Inn at 1740 N. First St. The conference
will focus on the range of emerging psychedelic drugs and the
burgeoning scientific fields of study that are springing up around
them. Dozens of speakers will attend, including Weiland Ralph
Metzner, who have been leaders in the field since the 1960s, and
Carolyn "Mountain Girl" Garcia, widow of the late Grateful Dead
guitarist, "Captain Trips" himself. It will also feature less-well
known presenters exploring the clinical, spiritual, therapeutic and
social applications of psychedelics.

Weird Science

The alternative medicine guru Dr. Andrew Weil, who began his career
in the 1960s as a psychedelic researcher and wrote several popular
books on the subject, says people have always used certain drugs "to
allow them to transcend their human and ego boundaries, to feel
greater contact with the supernatural, or with the spiritual, or with
the divine, however they phrase it.

"Drugs don't have spiritual potential," he says, "human beings have
spiritual potential. And it may be that we need techniques to move us
in that direction, and the use of psychoactive drugs clearly is one
path that has helped many people."

Weil, who will attend the conference this weekend, was a colleague of
Timothy Leary and Richard Alpert at Harvard, where the three men
rocked academia with their studies. At that time, LSD was legal­but
that changed quickly. After a brief public debate about its potential
merits, LSD was outlawed in 1966.

Leary, who had by then become "the Psychedelic Messiah," was not
surprised by the development.

"The effect of consciousness-expanding drugs will be to transform our
concepts of human nature, of human potentialities, of existence,"
Leary said. "These possibilities naturally threaten every branch of
the establishment. The dangers of external change appear to frighten
us less than the peril of internal change. LSD is more frightening
than the Bomb!"

After decades of social marginalization and governmental suppression,
there is a renaissance going on in the world of psychedelic research.
In 2010, there are as many research projects on mind-altering drugs
going on as there were in the late 1960s, before the U.S. government
started cracking down on them. But Summer of Love redux this is not.

Having learned from the mistakes of the acidheads of that era,
today's psychedelic community might be better prepared to deal with
some of the most powerful substances on earth.

There are promising studies under way around the world into the use
of psilocybin for cancer patients, MDMA for autism and Asperger's
syndrome, as well as ibogaine for addiction and LSD-assisted
psychotherapy for the treatment of anxiety associated with terminal
illness. Still, MAPS and the broader psychedelic community aren't out
of the woods yet. It took the researchers at MAPS five years of
fighting and navigating the bureaucracy of the Drug Enforcement
Agency and Food and Drug Administration to get their most recent, and
widely hailed, study under way.

Michael Mithoefer's 7-1/2-year, $2.2 million trial study into the use
of MDMA (Ecstasy) in the treatment of post-traumatic stress disorder
(PTSD) was the first legal pilot study of its kind in the United
States in decades and has been widely hailed by the medical community
a breakthrough in psychedelic research.

Despite the DEA putting up roadblocks at every turn, Mithoefer's
MAPS-funded research will be expanding this summer into the MDMA
treatment of Iraq war veterans' PTSD. Mithoefer's presentation is one
of the most highly anticipated talks of the San Jose conference.

What a Long, Strange Motherboard It's Been

It's a poetic coincidence that this week's MAPS conference is taking
place in the heart of Silicon Valley. Many of John Gilmore's
contemporaries­the engineers and entrepreneurs who created the
digital revolution­were inspired by the use of psychedelics in their
formative years.

Apple Inc. CEO Steve Jobs is probably the most candid of the Silicon
Valley pioneers on the subject of his drug use. He has called taking
LSD and traveling in India in the early 1970s "one of the two or
three most important things I have ever done in my life."

Jobs' former partner Steve Wozniak has also discussed his
experimentation with psychedelics, as have Microsoft CEO Bill Gates
and Lotus founder Mitch Kapor. Bob Wallace, the early Microsoft
employee who went on to found Quicksoft and coined the term
"shareware," is known as an "online drug guru" and donated generously
to MAPS and other psychedelics research before his death in 2002.

Programmer Mark Pesce, one of the early developers of the Virtual
Reality Modeling Language, says he was inspired by an LSD experience,
as was Douglas Engelbart, inventor of the first mouse prototype at
the Stanford Research Institute in 1963.

While Stanford grad-student Ken Kesey and his Merry Pranksters were
tripping with the Grateful Dead in San Francisco and in the hills
above Palo Alto, tech heads were exploring the world of mind-altering
substances in a different way. The stimulating blend of technology
culture and the psychedelic culture that emerged in Silicon Valley in
that era of change continues to impact the evolution of technology.
The list of influential locals who were inspired by psychedelics goes
on and on, and it isn't just limited to the world of high tech.
Former state senator and Assembly Ways and Means chairman John
Vasconcellos, who represented San Jose for 38 years, says that he too
experimented.

"I'm curious," says Vasconcellos of his psychedelic drug use, "but
I'm also not a dumb guy. I asked the experts, read the books and knew
what dangers there were with any of them and what conditions made it
far less risky, if at all. I was shrewd, and don't think I ever did
anything that might have gotten me in trouble. And as far as I know,
it didn't."

Vasconcellos, who is a MAPS supporter, has been a major figure in the
effort to reform the laws on drug abuse and prevention. He says that
his drive to make intelligent, informed drug policy in this country
goes back to 1968, when he first sat in on a drug conference at the
Santa Clara Valley Medical Center. There, he was surprised to learn
from presenters that marijuana is chemically not a narcotic, despite
how it was defined by law at the time. This discovery prompted him to
spearhead one of his first bills.

"I put a bill in that took away all the marijuana positions word by
word and moved it out of the narcotics section, into a special
section," he says. "It didn't change the penalty, it doesn't say it's
OK. It just said call it what it is, and people acted like it was the
end of the world. I just wanted the law to be honest, so it was respectable."

Vasconcellos will be attending this week's MAPS conference. He says
that he's excited to learn about the new developments in the world of
psychedelics research.

"I think what MAPS stands for is an enlightened approach to the facts
and to promote well-informed choices by the public," he says. "We
need a government that helps its people understand what their choices
are, rather then trying to hoodwink them into thinking things are
more dangerous then they are, or less dangerous than they are."

Ritual High

The first ceremony begins at dark. The participants come into the
octagon spiritual room in the middle of the Amazon rainforest. They
sit in a circle and state their intentions about what they want out
of the ceremony. The more specific the question they want answered,
the better.

The doses of ayahuasca are handed out in small cups. Everyone drinks
it together, most wincing at the acrid taste that has been likened to
"the entire jungle ground up and mixed with bile." As soft tribal
music plays in the background, everyone lies down. They focus their
attention and wait.

Ayahuasca is not the kind of psychedelic that one takes to go dancing
at a party. A tea derived from two vines that grow in the Amazon
jungle, this powerful psychoactive causes intense nausea in most
people. It also catapults its users into an intense, introspective
psychedelic experience that many feel is capable of curing addiction,
anxiety and depression.

Deborah Quevedo, a San Jose resident who has attended more than 50
ceremonies in South America, says the ayahuasca experience is like a
"psycho-spiritual purging of past traumas."

Users are immersed in a visionary experience that lasts four to six
hours. Many people experience insights; they may relive parts of
their lives or see parts of their childhood they had forgotten, Quevedo says.

Over the last decade, ayahuasca has become a favorite among the
psychedelic community. Also called yage, it is the very same plant
that the beat writer William S. Burroughs sought out while
corresponding with poet Allen Ginsberg in The Yage Letters.

Since the 1990s, there has been an upswing in the establishment of
neoshamanic retreats in Brazil, Peru and Ecuador. More and more
Westerners are traveling to South America with the intent of
undergoing these psychedelic experiences for personal growth and healing.

An entire track of the upcoming MAPS conference is dedicated to
presentations and discussions on ayahuasca, and its active ingredient
dimethyltryptamine (DMT).

Long used by natives in the Amazon basin for healing and divination,
the drug can currently only be used in the United States by members
of the União do Vegetal (UDV) and Santo Daime churches, both of which
have won Supreme Court battles in the last three years.

"The interesting thing about ayahuasca is that's it's really let the
faith community kind of blossom into the psychedelic community,"
Gilmore says. "It's brought in people who were more interested in the
metaphysics or religion and the direct experience of God. I think
with the validation in the Supreme Court helped also. They
established that, yes, this really is a religion, and they get to use
their sacraments the same as Native Americans and their peyote ceremonies."

Quevedo will be presenting her own graduate-school research on
ayahuasca at the conference. She and her husband have worked for
decades in the fields of holistic and alternative healing at O'Connor
Hospital in San Jose, Stanford University Medical Center and UCSF
Medical Center.

"We had heard all kinds of interesting reports about ayahuasca being
effective in the treatment of addictions," she says.

The Quevedos made their first trip to a Brazilian ayahuasca retreat
in 2001 to experience the drug themselves. "It was really
life-changing for me," she says. "I had never had any experience with
any mind-altering substances before, so it was all new and very expansive.

"I came home from that retreat when I was starting a Ph.D. I
basically spent the next six years of my graduate school trying to
figure out what had happened to me."

Drugs Against Drugs

Brian Anderson is a Stanford University medical student who is
presenting his own independent scholarly project on ayahuasca at the
MAPS conference. Drawing from his own research, Anderson says he has
seen evidence that ayahuasca "really works" in the treatment of addiction.

"I think a lot of other medical professionals are starting to reach
into this literature," he says. "They say this is a good reason we
should investigate these substances in controlled trials, in a more
medical setting here in North America."

Randolph Hencken, MAPS director of communication and the main
organizer of this week's conference, says it wasn't a Brazilian vine,
but an African shrub that cured his addictions. In his early 20s,
Hencken says, he was a heroin addict.

"I'd been a junkie for four years," he says. "I'd pissed off my
family, I'd pissed off my friends. I didn't like myself anymore, but
it was easier to keep using heroin."

After he tried 12-step programs and methadone clinics, Hencken heard
about ibogaine. While it has long history of use in African spiritual
rituals, there is also a large international underground movement of
people using the drug to treat addiction. Desperate, Hencken made the
trip down to Mexico City in 2001 to take capsules of the drug with a
doctor (ibogaine is currently illegal in the United States).

"It wasn't a fun trip," Hencken says. For more than 24 hours he
experienced ataxia, rendering him unable to move as the substance's
psychoactive effects took hold, bringing with it visions from
throughout his life. "I don't think I had any epiphanies that day,"
he says, "but it did stir up all these things I was suppressing about
my childhood that were interrelated as to why I was a drug addict."

Hencken says he has been clean for nine years. Since then he has
earned degrees from San Diego State University and is dedicated to
spreading the word about alternative drugs.

"Getting through something that is so mentally tough, I think gave me
some strength," he says. "It made me confident that if I could get
through that, then I can stay away from using heroin."

Demon Dots

If human beings are set apart by their ability to design and use
tools, then, in a way, psychedelic drugs are a form of technology.
Whether they be synthetically synthesized substances like MDMA or
LSD, or naturally occurring drugs like psilocybin and mescaline,
psychedelics can be viewed as a tool for the brain to be able to tune
into diverse states of consciousness.

Considering the extraordinary power of psychedelic drugs, it's not
shocking that when LSD and other mind-altering substances first
appeared in the mainstream in the 1960s, some people were terrified.
A mere 50 micrograms of acid, an amount that could fit onto the head
of a pin, can have a profound effect on the brain's function and
launch a person into a full-blown psychedelic experience.

"What we often hear from the media is that psychedelics will bring
out your demons and make you go crazy," Hencken says. "Or, they'll
give you schizophrenia or you'll jump off the roof­things that have
only really happened to a very few people. I think the bulk of
people, if they have these experiences and do them in the right
setting, they'll find them to be very beneficial to their lives."

The late Laura Archera Huxley, a psychedelic advocate and wife of
Brave New World and Doors of Perception author Aldous Huxley, once
said that a person can get out of psychedelics in one night what they
could get from a psychotherapist in several years. As an
organization, MAPS would like to see psychedelics accepted to the
point that they can be administered safely.

"I first did psychedelics when I was in high school, and I remember
friends taking friends to go tripping in a grave yard," Hencken says.
"That's a terrible place to go tripping. You're opening yourself up
to a situation where you're going to see dead people, and you're
going to freak out. A lot of people choose terrible places to do
these drugs for the first time."

Hencken says that the bulk of the "bad trips" that people experience
on psychedelics could be prevented if the drugs were regulated and
the users were properly informed about how to conduct a safe trip.

"Ideally, MAPS would like to see a situation in the near future where
people who are interested in these drugs can get honest information.
Where they can get unadulterated, clean, safe drugs, and they can do
them with a guide that understands the power of these things."

Though next week's conference, MAPS and its allies aim to present a
spectrum of examples of psychedelics' worth. By re-examining what
casual explorers, scientists, religious leaders and others have
learned during the decades since these substances have been discussed
in a public forum, the psychedelic community endeavors to find a
valid social accommodation.

"I think that process has only just begun," says John Gilmore.
"Researchers need to continue to learn both about how psychedelics
work in the brain, and how they can be used to heal brains that don't
work perfectly. We're just in the infancy of all of this, and I
expect to see a lot of people live better lives in the future thanks
to psychedelics."

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1 comments:

Billy Lenox said...

DMT is certainly a curious experience. Chapter 4 of my on-going on-line novel "Summer of '85" details one character's experience on this remarkable substance. Check it out at www.summerof1985.wordpress.com. Thanks, dude, for this awesome blog.